Research Progress on Antibacterial Coatings for Preventing Implant-Related Infection in Fractures: A Literature Review

Implant-related infection is a difficult problem in orthopaedics as it not only leads to failure internal fixation, but also increases the financial burden and perioperative risk on patients. In past, orthopaedic implants were designed mechanical fixation devices simply maintain biological properties, regulate surrounding microenvironment. More recently, antimicrobial biocoatings have been incorporated into prevent treat implant-related infections through modulation of local environment. This article reviews application orthopaedic-implant biocoating prevention implant-caused infection. Although there are many candidate coatings, they still preclinical testing stage, thus additional research by biomaterials clinicians necessary identify ideal implant coatings for patients who require fracture surgery.